Thursday, August 1, 2013

US Cellular opens Moto X pre-orders for $199 with free Motorola headset

Moto X

'Switcher Bonus' knocks $75 off the price for new activations.

U.S. Cellular is jumping on the bandwagon of Moto X news today by announcing its own pricing, availability and deals for the handset. Just as is the case with the other carriers, U.S. Cellular will have both the black and white Moto X in 16GB capacity for $199 on-contract (and an oddly-high $699 off-contract). The carrier is also offering a $75 "Switcher Bonus", which knocks the on-contract price to $124 for new activations.

Additionally, U.S. Cellular is actually putting the device up for pre-order today, letting you lock in your device while the other carriers simply have announcements up. Customers who pre-order will also get a Motorola Boom Bluetooth headset, valued at $59.99.

A specific launch date is not yet known, but latest leaks point to the last week of August.

More: U.S. Cellular Pre-orders

read more

    


Source: http://feedproxy.google.com/~r/androidcentral/~3/NES28kSzzRI/story01.htm

Chris Lighty JJ Watt jerry sandusky hayden panettiere raul ibanez completely wrong stacey dash

08/01/13 RTIR E-zine: Bradley Manning, Internet ... - RTIR Online

August 1, 2013

01. Sentencing Bradley Manning
02. Peace Prize for Manning?
03. Forgiving Anthony Weiner
04. Is Salad Safe?
05. Cheap, End-of-Summer Fun
06. Pack Your Travel Smarts
07. Where Internet Predators Lurk
08. Hurricanes, Tornadoes & Summer Disasters
09. More American Families Homeless
10. Top 5 Interview Blunders
11. How to Talk at Work
12. She Built a $5M Business in 18 Months
13. Zimmerman Trial ? Spark that Ignited
14. Feng Shui of the Royal Family Tree
15. Can Clutter Make You Sick?
16. Former Actress on Facing Cancer with Grace
17. Can You Choose to Be Happy?
18. Summer Pet Safety
19. Astrologer on Hollywood Cold Cases
20. He?s the Ultimate Party Authority

=======================================

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01. ==> Sentencing Bradley Manning

According to Gabriel Schoenfeld of the Hudson
Institute, Bradley Manning betrayed America, broke the
law, and needs to be punished. ?Our government is
acting fully within its rights and with justice on its
side when it punishes someone who betrays his oath,
abuses his position of responsibility in a way that
weakens our country and imperils friends and allies
around the world.? He adds, ?The indiscriminate mass
leaking that Manning engaged in was recklessness of a
high order. However much one wants to temper justice
with mercy when a young person commits a crime, it?s
Manning?s recklessness that demands he face a harsh
sentence.? Gabriel Schoenfeld is a senior fellow at the
Hudson Institute, a policy research center that
describes itself as working to promote national and
global security and freedom. He is the author of
?Necessary Secrets: National Security, the Media and
the Rule of Law,? and ?A Bad Day on the Romney
Campaign: An Insider?s Account.? Contact him at
schoenfeld.g@gmail.com; @gabeschoenfeld or James
Bologna at (202) 974-6456; jbologna@hudson.org

02. ==> Peace Prize for Manning?

Despite a judge finding him guilty of 20 counts -
include violations of the Espionage Act ? Norman
Solomon says Bradley Manning should get the Nobel Peace
Prize. ?Thanks to Manning, vast troves of information
have become public knowledge, making possible more
informed debate about war and peace. For instance, he
leaked the now-infamous ?collateral murder? video, with
a soundtrack of chilling banter as U.S. servicemen in a
pair of gunships fired on civilians in Baghdad.?
Solomon says he?ll deliver a petition to the Nobel
Committee in Oslo next month, with more than 100,000
signatures. Norman Solomon is founding director of the
Institute for Public Accuracy and author of ?War Made
Easy: How Presidents and Pundits Keep Spinning Us to
Death.? He?s the co-founder of RootsAction.org, which
organized the petition. Contact him at (415) 488-3606,
solomonprogressive@gmail.com

03. ==> Forgiving Anthony Weiner

After admitting he sent more lewd messages to women
after his 2011 resignation from Congress, NYC mayoral
hopeful Anthony Weiner?s poll numbers plummeted, his
campaign manager quit, and questions keep coming about
his online relationships. Weiner vows to stay in the
race, and his wife, a top aide to Hillary Clinton, says
she?s forgiven him and New York voters should too.
Should she? Could you? Should voters? Lisa Gibson
considers herself a forgiveness expert. She lost her
brother in the 1988 bombing of Pan Am flight 103 over
Scotland and made headlines when she met ? and forgave
- Libyan leader Muammar Gaddafi, one of the world?s
most notorious terrorist and man responsible for her
brother?s death. She?ll outline the five stages people
need to go through in order to forgive anyone and share
the life changing stories of others who have applied
these principles to their lives. Lisa is a terrorism
expert who does conflict resolution training in war
torn countries like Afghanistan, Libya, Iraq and Sudan.
She?s been featured on CNN, MSNBC, NBC, ABC, CBS, and
countless other networks and has written ?Releasing the
Chains: Timeless Wisdom on How to Forgive Anyone for
Anything? and ?Life In Death: A Journey from Terrorism
to Triumph.? Contact Lisa Gibson at (720) 839-3285
(CO); lisa@peaceandprosperityalliance.org

04. ==> Is Salad Safe?

Prepackaged salad is believed to be behind a cyclospora
outbreak that?s sickened hundreds across the country
over the past few weeks. Hundreds of people have been
affected in 16 states with almost two dozen
hospitalized. Health officials say the threat is gone
and people should still eat their fruits and veggies,
but they advise washing everything thoroughly. Jon
Frank says washing may help get rid of some health
threats, but you may still consume toxic residue and
eat food that has fewer nutrients, all because of the
way most produce is grown today. You?ll hear why
locally grown and organic produce may not be healthier
options, which minerals are missing from most produce,
how toxic residues reduce absorption of nutrients, and
health issues caused by the unlabeled genetically
modified foods you?re eating. Jon Frank owns a soil
testing lab and educates gardeners and large-scale
growers nationwide on how to produce nutrient dense
produce. His new book is ?Grow Your Own Nutrition: How
to Opt Out of Toxic Agriculture.? Contact him at (507)
236-9076 (MN); jon.frank@aglabs.com

05. ==> Cheap, End-of-Summer Fun

Looking to keep the kids occupied, have some summer
fun, and stay on budget? ?No problem,? says Denise
Winston. Invite the financial expert Readers Digest
calls one of the Cheapest People in America to talk
about ways to sneak in some fun this August, without
breaking the bank. Denise has lots of great ideas for
getting the whole family involved in planning ? and
paying ? for activities. You?ll learn where to find
inexpensive ? or even free ? workshops and classes, and
how giving back to others can bring great rewards.
Denise is a former banker and the author of ?Money
Starts Here! Your Practical Guide to Survive and Thrive
in Any Economy.? Contact her at (661) 333-5247 (CA);
denise@MoneyStartHere.com

06. ==> Pack Your Travel Smarts

Cubicles everywhere are empty but airports and highways
are hopping! It?s summer travel season, and Hon. Nancy
Steorts, a safety expert and former head of the U.S.
Consumer Product Safety Commission says travel is
exciting and fun, but you need to keep your wits about
you, and be smart. She?ll tell you the safest clothes
to wear on a plane and explain how simple things, like
noting your hotel?s emergency exits, could save your
life should you find yourself in a ?situation.? She
says women, in particular, should only use their first
initials and last names when making reservations and
checking in. ?And make sure the hotel clerk does not
announce your room number. If it happens, request a new
room.? She?ll also share a safety checklist on how to
keep your house safe while you?re away. Nancy Steorts
is the author of several books including ?Your Home
Safe Home.? Steorts has appeared on national networks
including ABC, CBS, NBC, CNN, MSNBC, and Fox News.
Contact her at (240) 401-7782 (VA);
nancysteorts@cox.net

07. ==> Where Internet Predators Lurk

Millions of us use the Internet every day for shopping,
emailing, connecting ? it?s a great resource but it?s
also the perfect avenue for predators waiting to take
advantage of their next victim. Cyberstalking expert
Jayne Hitchcock, a victim herself, will explain how
criminals use the Web to stalk victims, bully them,
extort them out of money and even target them as
victims of violent crime. You?ll learn where the bad
guys are most likely to get your information, why you
should always lurk before posting a comment, and how to
make sure your kids don?t become targets. Jayne
Hitchcock has appeared on numerous major network news
shows. She?s the president and co-founder of WHOA
(Working to Halt Online Abuse) and conducts law
enforcement training and school presentations about the
importance of Internet safety. Contact Rob Colding at
(609) 654-6266, ext. 330(ME); rcolding@infotoday.com

08. ==> Hurricanes, Tornadoes & Summer Disasters

It?s August, and prime season for some intense weather
around much of the country. Invite disaster
preparedness expert Dr. Arthur Bradley on your show to
share tips your listeners need to get through the rest
of summer, whether they?re in tornado alley or in
coastal areas prone to hurricanes. ?Most Americans
simply don?t appreciate that the United States
experiences more dangerous weather than any other
country in the world. It isn?t until winds are blowing
and rain is pounding that they begin to think about
their vulnerability. Unfortunately, by then, it is
often too late.? He?ll detail how to avoid what he
calls the Five Horsemen of Death and what everyone
should have on hand at all times, at home and in their
car. Arthur Bradley, Ph.D. is the author of ?Handbook
to Practical Disaster Preparedness for the Family and
the Prepper?s Instruction Manual.? Contact him at (757)
332-0829

09. ==> More American Families Homeless

Right now, one in five American children lives in
poverty and family homelessness in the United States
has increased more than 20 percent since the recession
began in 2007. Ralph da Costa Nunez, Ph.D., president
of the Institute for Children, Poverty and
Homelessness, has worked closely with homeless families
for more than two decades. He?ll discuss why there are
nearly 1 million homeless students in public schools,
why you should talk to your children about poverty and
homelessness, why simply building housing isn?t the
answer, and what can be done in your community to help
break the cycle of family and child homelessness. Dr.
Ralph Nunez is former deputy director for the New York
City Mayor?s Office of Homeless and Housing Services
and a professor at Columbia University. He?s the author
of ?A Shelter is Not a Home? Or is it? ? Revisited? and
numerous publications. Contact Linda Bazerjian at (212)
358-8086, ext. 1204 (NY); Lbazerjian@ICPHusa.org

10. ==> Top 5 Interview Blunders

You got the interview and waited to hear back but ?
nothing. What happened? According to interview coach
and recruiting expert Stuart Taylor, most people are
disqualified early on for any number of avoidable deal
breakers, including not knowing enough about a company,
fumbling on a response, a poor handshake, or even
forgetting to ask for a business card. Taylor advises
job candidates to approach the interviews the same way
you would a date. He?ll reveal the top 5 mistakes
people make, rules for a great interview, and how to
avoid the ?last second? mistakes that can derail one.
Taylor is the author of ?How to Ace a Job Interview.?
Contact him at (323) 974-7353 (MD);
stuart@topperformers.com

11. ==> How to Talk at Work

Shawn Kent Hayashi works with Fortune 500 companies to
help their employees learn how to communicate
effectively and collaboratively ? even when their
personalities, priorities and work styles are miles
apart. You?ll learn 12 conversations you can use in any
work situation and how to get workplace conversations
back on track ? even when they seem to be veering out
of control. She?ll share how changing the way you talk
with peers, employees and bosses can move your career
forward and help you motivate others and get results.
Shawn Kent Hayashi is an executive coach, keynote
speaker and the founder of The Professional Development
Group. Her latest book is ?Conversations that Get
Results and Inspire Collaboration.? Contact her at
(215) 588-1188 (PA);
Shawn@TheProfessionalDevelopmentGroup.com

12. ==> She Built a $5M Business in 18 Months

Did you know that more than 12 percent of U.S. adults
started or ran a new business last year? While millions
of Americans are eager to join their ranks, running a
successful small business is much more challenging than
most entrepreneurs expect. Interview business start-up
expert Niki Pfeiffer to learn what she did to grow her
start-up business. ?So many businesses fail because the
business tries to be everything to everyone or spread
itself too thin. Business success is more about what
you say ?no? to rather than what you say ?yes? to.? A
business strategist who has worked with many Fortune
500 companies, Niki Pfeiffer created a multimillion-
dollar technology business in just 18 months and is the
inventor of the Wine Gabby wine carrier. Contact her
at (610) 805-5803 (PA); npfeiffer@nikipfeiffer.com

13. ==> Zimmerman Trial ? Spark that Ignited

The George Zimmerman verdict has further divided
America on the issue of race, but many people are
missing key factors driving this nationwide emotion.
According to Sandra and Daniel Biskind, the spike in
anger and frustration isn?t just about this event. They
say the big picture goes way back. ?The not guilty
verdict has triggered a flood of ancient anger,
frustration and despair. When a tragedy like this
occurs, we can?t ignore the feelings we try to deny
every day; we are afraid we don?t belong in this world
with the people we find as our neighbors.? Sandra and
Daniel Biskind are spiritual life coaches who?ve
appeared on numerous radio shows and in magazines
throughout Australia and New Zealand. Their upcoming
book is ?The Forgiveness Principles.? Contact them at
(310) 658-8406; biskind@heartpower.net

14. ==> Feng Shui of the Royal Family Tree

Little Prince Georgie is third in line to be King,
behind Grandpa Charles, and his dad, William. Just like
an episode of Downton Abbey, we love the pomp and
circumstance of the Royal Family along with the cast of
characters. Bring Patt Sendejas on your show to talk
about the dynamics of the family by analyzing their
Feng Shui personality styles. She?ll explain the
relationship between Kate and the Queen, the success of
Kate and William?s marriage, and why Princess Di and
the Queen didn?t get along. She?ll also reveal how this
new edition to the family tree will change things. She
says it?s no surprise Prince Harry loves to play and
will make a great uncle. Patt Sendejas is the author
of several books including her latest, ?Live Your Life
on Purpose ? Discover Your Feng Shui Personality Type:
The People & Spaces that Support You? Contact her at
(805) 523-8488; pat@speaker4change.com

15. ==> Can Clutter Make You Sick?

Organizing expert Dorothy Breininger says most people
don?t realize the ill effect clutter is having on them.
She says summer is the perfect time to take a hard look
at your garage, basement, closet and everywhere in-
between where things accumulate. She?ll explain what
your clutter says about you if you have too much paper,
too many clothes, too much food, or too many books, and
the link between clutter and weight gain, unhappiness
and poor health. Dorothy Breininger is seen on A&E?s
Hoarders series and has appeared on the Today show, Dr.
Phil, The View, Oprah and other programs. Her latest
book is ?Stuff Your Face or Face Your Stuff.? Contact
Kim Weiss at Kimw@hcibooks.com

16. ==> Former Actress on Facing Cancer with Grace

Former All My Children actress Mary Ann Wasil was
diagnosed with breast cancer in 2004. She?ll share her
personal story and how she?s faced her battle with
grace, style and faith ? even if it means wearing
stilettos to her chemotherapy appointments and paying
her doctors in warm donuts and gerbera daisies. Invite
her to hear what it?s really like to be a cancer
patient, why a diagnosis isn?t a death sentence and why
she calls the years since her diagnosis the happiest of
her life. Mary Ann Wasil was 39 years old and the
single mother of three when diagnosed with cancer.
She?s since become a health activist, speaker, and the
author of ?A Diary of Healing.? She?s also the founder
the nonprofit Get In Touch Foundation. Contact her at
(203) 913-7773 (CT); mediarequets@maryannwasil.com

17. ==> Can You Choose to Be Happy?

We?ve all seen them; those people who always seem
upbeat, happy and hopeful, even when those around them
aren?t. What?s the secret? Rico Racosky says they
choose to be that way and he?ll explain how anyone can
transform their own attitude. Rico says we?re
conditioned to think happiness is elusive, rare or even
unnatural, but in reality, happiness is there for the
taking, if you decide to grab it. You?ll learn how
happy people keep smiling despite a struggling economy,
workplace or personal issues, and even the weather!
When he?s not flying planes, Rico Racosky writes
motivational books for kids and adults. His latest is
?Just2Choices ? It?s that Simple.? Contact him at (303)
442-0324 (CO); rico@just2choices.com

18 ==> Summer Pet Safety

From pests to heatstroke, pets face a whole host of
dangers in summertime. Bring Dorie Miller on your show
and learn the top five critters that pose the greatest
danger to your dog, how your pup?s teeth could be most
at risk during the summer months, and what happens when
you leave your pet outside ? even when the heat?s as
low as 70 degrees. Dorie Miller founded The Marley
Foundation after her beloved dog, Marley, was bitten by
a rattlesnake while on a hike. After a two-mile sprint
to an emergency clinic, Marley was able to recover from
the poisonous bite. Now, Dorie?s on a mission to
educate others on the hazards pets face in the summer
months. The Marley Foundation is a fund that helps
people pay for emergency veterinary care. Contact Dorie
Miller at (608) 520-4632 (WI);
dorie@changeunlimited.com

19. ==> Astrologer on Hollywood Cold Cases

Can the stars in the sky shed light on the mysteries
surrounding Hollywood?s brightest stars? Forensic
astrologer B.D. Salerno says yes?and she?ll discuss her
shocking findings with your audience. Ask B.D. whether
Marilyn Monroe?s death was really a suicide, if Natalie
Wood fell off that boat, and who the stars say is the
real culprit in JonBenet Ramsey?s murder. B.D. will
also discuss how the positions of stars and planets
reveal clues about the mysterious deaths and
disappearances of ordinary folks all across the
country. B.D. Salerno has been an astrologer for 20
years and has worked with investigators on missing-
persons cold cases. She is developing methods for the
astrological profiling of criminals and is the author
of ?Forensics by the Stars: Astrology Investigates.?
Contact Grace Allen at (888) 795-4274;
grace.allen@iuniverse.com

20. ==> He?s the Ultimate Party Authority

Staging an event is never easy, just ask Darren
Johnson, the nation?s top corporate event planner. He?s
the guy Microsoft, Disney, Universal Studios and Coca
Cola call to make their events special. Johnson has a
behind-the-scenes tale for the biggest and splashiest
parties he?s produced; And while nearly every story has
a happy ending, some of the moments leading up to them
are painful, unwelcome and truly terrifying. Surprises
like charging rattlesnakes, sprinklers going off during
outdoor receptions, and power outages at night. He?ll
share must-know rules to producing a killer event for
100 guests or 10,000. Johnson has produced more than
4,000 corporate and sport events throughout North
America and has appeared on NBC, ABC, CBS, FOX, CNBC,
in the Miami Herald, and in several online news
magazines. His new book is ?Going Live: Insider Secrets
to Corporate Event Production. Contact him at (352)
205-6866 (FL); darren@dwj-p.com

Source: http://www.rtironline.com/2013/08/01/080113-rtir-e-zine-bradley-manning-internet-predators-royal-family/

2 Chainz Big Brother 15 BET AWARDS 2013 Yarnell Az Arizona fire cirque du soleil Confederations Cup

NIH launches neurological drug development projects

NIH launches neurological drug development projects [ Back to EurekAlert! ] Public release date: 31-Jul-2013
[ | E-mail | Share Share ]

Contact: Christopher Thomas
thomaschr@ninds.nih.gov
301-496-5751
NIH/National Institute of Neurological Disorders and Stroke

New projects will target Fragile X syndrome, nicotine addiction, and age-related macular degeneration

The National Institutes of Health has launched three innovative projects that will focus on development of therapeutics for Fragile X syndrome, nicotine addiction, and age-related macular degeneration (AMD). These projects are funded through the NIH Blueprint Neurotherapeutics Network which provides access to a variety of drug development resources.

"We are excited about the opportunity to apply cutting-edge science to the pursuit of novel treatments for these debilitating disorders" said Rebecca Farkas, Ph.D., program director at NIH's National Institute of Neurological Disorders and Stroke (NINDS), Office of Translational Research.

The purpose of the NIH Blueprint is to provide in-depth research capabilities to increase the success rate of innovative drug discovery efforts. The program uses a virtual pharma model to provide researchers with access to support and resources that have been traditionally available to large pharmaceutical companies.

Partnerships between NIH program staff and awarded research teams are designed to bridge the funding gap between ground-breaking laboratory research and industry adoption. NIH staff helps investigators work with veteran industry drug development consultants and contract research organization capabilities from the discovery stage through preliminary clinical trials. In addition, each investigator maintains sole ownership of intellectual property associated with his or her project

NIH launched the Blueprint Neurotherapeutics Network in 2011. Including these three awards, 14 drug discovery programs have been funded as part of the program and 10 are currently active (see: http://neuroscienceblueprint.nih.gov/bpdrugs/bpn.htm).

The newly-funded investigators and their organizations are:

  • Sage Therapeutics, Cambridge, Mass.
    Principal Investigator: Al Robichaud, Ph.D.
    Disorder: Fragile X syndrome
    Project Summary: Fragile X syndrome is a genetic disorder linked to a range of neurodevelopmental disorders including learning disabilities and cognitive impairment. Many patients experience general and social anxiety yet benzodiazepines, which are drugs typically used to treat anxiety disorders, provide little relief. Their anxiety has been linked to reduced activity in the brain by a protein called, the GABA A receptor. Sage Therapeutics is developing positive allosteric modulators, designed to enhance the receptor's activity and possibly relieve the anxiety.
  • The Scripps Research Institute, Jupiter, Fla.
    Principal Investigator: Paul J. Kenny, Ph.D.
    Disorder: nicotine addiction
    Project Summary: Nicotine addiction has been attributed to the stimulatory effects of nicotine binding to brain proteins called orexin 1 receptors. Dr. Kenny and colleagues will develop selective receptor antagonists as potential smoking cessation aids to treat people who have attempted to quit smoking but faced high relapse rates and significant side effects.
  • University of Utah, Salt Lake City
    Principal Investigator: Dean Yaw Li, Ph.D.
    Disorder: age-related macular degeneration
    Project Summary: Age-related macular degeneration is a leading cause of blindness in the United States. One form, called wet AMD, is associated with inflammation and blood vessel leakage in the retina, the eye's light-sensitive tissue. Dean Li and his colleagues are developing small molecules that inhibit the activity of Arf6, a molecule known to help control inflammation and blood vessel leakage. This novel approach may lead to effective therapies for treating patients who do not respond to current wet AMD therapies.

###

NINDS is the nation's leading funder of research on the brain and nervous system. The NINDS mission is to reduce the burden of neurological disease a burden borne by every age group, by every segment of society, by people all over the world.

About the National Institutes of Health (NIH): NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit http://www.nih.gov.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


NIH launches neurological drug development projects [ Back to EurekAlert! ] Public release date: 31-Jul-2013
[ | E-mail | Share Share ]

Contact: Christopher Thomas
thomaschr@ninds.nih.gov
301-496-5751
NIH/National Institute of Neurological Disorders and Stroke

New projects will target Fragile X syndrome, nicotine addiction, and age-related macular degeneration

The National Institutes of Health has launched three innovative projects that will focus on development of therapeutics for Fragile X syndrome, nicotine addiction, and age-related macular degeneration (AMD). These projects are funded through the NIH Blueprint Neurotherapeutics Network which provides access to a variety of drug development resources.

"We are excited about the opportunity to apply cutting-edge science to the pursuit of novel treatments for these debilitating disorders" said Rebecca Farkas, Ph.D., program director at NIH's National Institute of Neurological Disorders and Stroke (NINDS), Office of Translational Research.

The purpose of the NIH Blueprint is to provide in-depth research capabilities to increase the success rate of innovative drug discovery efforts. The program uses a virtual pharma model to provide researchers with access to support and resources that have been traditionally available to large pharmaceutical companies.

Partnerships between NIH program staff and awarded research teams are designed to bridge the funding gap between ground-breaking laboratory research and industry adoption. NIH staff helps investigators work with veteran industry drug development consultants and contract research organization capabilities from the discovery stage through preliminary clinical trials. In addition, each investigator maintains sole ownership of intellectual property associated with his or her project

NIH launched the Blueprint Neurotherapeutics Network in 2011. Including these three awards, 14 drug discovery programs have been funded as part of the program and 10 are currently active (see: http://neuroscienceblueprint.nih.gov/bpdrugs/bpn.htm).

The newly-funded investigators and their organizations are:

  • Sage Therapeutics, Cambridge, Mass.
    Principal Investigator: Al Robichaud, Ph.D.
    Disorder: Fragile X syndrome
    Project Summary: Fragile X syndrome is a genetic disorder linked to a range of neurodevelopmental disorders including learning disabilities and cognitive impairment. Many patients experience general and social anxiety yet benzodiazepines, which are drugs typically used to treat anxiety disorders, provide little relief. Their anxiety has been linked to reduced activity in the brain by a protein called, the GABA A receptor. Sage Therapeutics is developing positive allosteric modulators, designed to enhance the receptor's activity and possibly relieve the anxiety.
  • The Scripps Research Institute, Jupiter, Fla.
    Principal Investigator: Paul J. Kenny, Ph.D.
    Disorder: nicotine addiction
    Project Summary: Nicotine addiction has been attributed to the stimulatory effects of nicotine binding to brain proteins called orexin 1 receptors. Dr. Kenny and colleagues will develop selective receptor antagonists as potential smoking cessation aids to treat people who have attempted to quit smoking but faced high relapse rates and significant side effects.
  • University of Utah, Salt Lake City
    Principal Investigator: Dean Yaw Li, Ph.D.
    Disorder: age-related macular degeneration
    Project Summary: Age-related macular degeneration is a leading cause of blindness in the United States. One form, called wet AMD, is associated with inflammation and blood vessel leakage in the retina, the eye's light-sensitive tissue. Dean Li and his colleagues are developing small molecules that inhibit the activity of Arf6, a molecule known to help control inflammation and blood vessel leakage. This novel approach may lead to effective therapies for treating patients who do not respond to current wet AMD therapies.

###

NINDS is the nation's leading funder of research on the brain and nervous system. The NINDS mission is to reduce the burden of neurological disease a burden borne by every age group, by every segment of society, by people all over the world.

About the National Institutes of Health (NIH): NIH, the nation's medical research agency, includes 27 Institutes and Centers and is a component of the U.S. Department of Health and Human Services. NIH is the primary federal agency conducting and supporting basic, clinical, and translational medical research, and is investigating the causes, treatments, and cures for both common and rare diseases. For more information about NIH and its programs, visit http://www.nih.gov.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-07/nion-nln073113.php

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Cooking With Babette

Still from Babette's Feast, 1987.

Still from Babette's Feast, 1987.

Courtesy of Panorama Film A/S/The Criterion Collection

Rare is the film that can make your mouth water. So rare, in fact, that when it happens?when a movie really gets food and cooking?it?s easy to gorge yourself on it, stretching lazily into the conclusion that nothing better could hope to exist. I made this error, for example, with Julie & Julia, the 2009 film in which Meryl Streep plays a buoyant Julia Child and Amy Adams an annoying food blogger?here was clearly the best movie about food ever made. My mistake was an honest one: Like many home cooks who approach cooking as a discipline demanding of study rather than a slapdash hobby, I immediately felt a certain affinity with Child?s joyful yet utterly serious devotion to her craft. I bought a copy of Mastering the Art of French Cooking, prayed that it would usher Julia?s warm spirit into my own modest apartment kitchen with each new stain on its pages, and felt the food-movie contest to be closed. But that was before I met Babette.

I watched Babette?s Feast for the first time about a month ago, and by the time the credits rolled, it was clear to me that reassessments would need to be made. To a degree that I couldn?t have imagined (and certainly more so than Julia), Babette articulates a cooking ethic?one of generosity, care, artistic integrity, and above all humility?that I have aspired to for many years. With the 1987 Oscar-winning film by Danish director Gabriel Axel joining the Criterion Collection this month, that ethic and the small, lovely story that conveys it are enjoying the grand presentation they deserve.

The plot of Babette?s Feast, which is set in late-19th-century Denmark, is so simple as to be nearly nonexistent. A French woman named Babette arrives in an ascetic rural Lutheran community seeking shelter. She is taken in by the spinster daughters of the town?s deceased patriarch, and she works quietly as a housemaid and cook for many years. One day she receives word that she has won 10,000 francs in a lottery back in France, and she arranges to cook a ?real French dinner? for the few (and increasingly querulous) residents remaining in the town to mark what would have been the 100th birthday of the patriarch. Though the sect?s members are wary of earthly pleasures, Babette?s exquisite, beautifully composed meal?featuring most memorably a dish of stuffed quails in puff pastry called cailles en sarcophage?ultimately brings the village together again.

And how couldn?t it? Real turtle soup, sparkling Veuve Clicquot, and baba au rhum would inspire just about anyone to sing hymns under the stars. Yet the sentimentality of Babette?s Feast is tempered by a certain seriousness?seriousness about fine cooking, of course, but also about the power a cook has to, as the sociologist Priscilla Parkhurst Ferguson points out in an interview on the Criterion edition, help transform consumers into a community, however briefly. But today, when caloric abundance is the rule rather than the exception, does a complicated, lovingly prepared meal still have the power to bring people together? To find out, I determined to recreate Babette?s pi?ce de r?sistance, the cailles en sarcophage, for a group of friends.

There are a few serviceable recipes for the dish floating around online; I chose the one that seemed richest, calling for homemade duck-fat puff pastry and a luscious fig and Madeira sauce along with the truffle- and foie gras-stuffed quails. True, my Styrofoam-packed shipment of the gourmet items from D?Artagnan lacked the romantic appeal of Babette?s seaborne delivery, but it was exciting to have a single $25 summer truffle in the house, much less a fridge full of foie gras, delicate little partially deboned birds, a rich duck-veal demi-glace, and fine puff pastry. Discerning readers will detect that at this point I?ve already compromised by cheating on a few steps?the store-bought demi-glace, for instance, and certainly the puff pastry, the homemade pursuit of which I abandoned when a chef friend informed me that it would take at least three days to do properly.

The first step was to marinate the quails in pricey Bual Madeira and a little cognac overnight, along with thyme and garlic (my additions). After that, the process of assembly was surprisingly easy, if fragile. To create the puff pastry nests, I needed circular cutting implements of 5- and 3-inch diameters, respectively?a martini glass and small prep bowl filled the role nicely. As anyone who?s worked with puff pastry in a hot kitchen knows, the fickle stuff demands to be rushed back into the freezer after just a few minutes of handling lest it become too sticky, so the cutting process was slow. But once complete, I had four nice rounds with smaller circular indentations in the middle. After the pastry baked and rose majestically, I used the indentations as a guide to gently cut out a neat hole in the center of each puff?voila, we had sarcophages! ?

130730_FOOD_BabettesFeastBuns

Photos courtesy of Cam McDonald

Next I turned to my baby birds. Having purchased them already cleaned and deboned save for the legs and wings, I really only had to stuff and truss them like toy chickens. Though relatively easy, I will offer the following observations: Foie gras does not slice well in a hot kitchen (producing lots of messy errors I had no choice but to eat), and truffles, though insanely delicious, smell kind of like spoiled milk when waiting in your fridge.

130730_FOOD_BabettesFeastTable

Photos courtesy of Cam McDonald

Now all that was left was the actual cooking. After a brief sear in duck fat and a careful roast in the oven, I tucked my birds in their nests with the richest sauce my pan has ever contained, including figs, white wine, homemade chicken stock, demi-glace, and more Madeira. Sitting on their white plates, my cailles were not nearly as elegant as Babette?s, but they were, in the words of a dinner guest, remarkable. (And at roughly $37 dollars a plate, that?s fortunate).

130730_FOOD_BabettesFeastDish

Photos courtesy of Cam McDonald

Was the result worth the effort and cost? Considered purely as an exercise in cooking, I?d say sure?the cailles were as rich, succulent, and delicious as advertised (though there is some small irony to be found in the fact that my guests were more vocally appreciative of the first-course vichyssoise, which cost something like $4 per person.) However, my relative success with Babette?s special dish is not the thing that I value most about that evening. Instead, it?s my role as a cook in relation to my guests that I keep thinking about as the flavors fade from memory.

During this dinner I spent a great deal of time in the kitchen, prepping the next course, opening more wine, and generally taking pleasure in the fact that my guests were enjoying themselves?my food and service, as the grist for the gathering, were more important than my constant presence. In this sensibility I share something fundamental with Babette, who cooks not to impress or to show off (indeed, she never appears in the dining room), but rather to facilitate the alchemy that transforms good food into great fellowship.

This is an ethic that is all too rare. We live in a food culture dominated by the notion that cooking is a performance art, something that you wow people with from behind the island of your open-concept kitchen as if you were the host of your own Food Network show. The covers of glossy cooking magazines exhort you to ?impress your friends? with this or that new technique, while ?celebrity chefs? by their very existence make the argument that a cook?s personality is more important than her food. This is the contemporary self-centeredness that makes Julie?s half of Julie & Julia so unbearable?she may master French cooking, but in the end, the only guest she?s interested in feeding is her ego.

Contrast that with Babette. My favorite scene in the film comes after the last, glistening course has been served, when she finally sits for a moment in the kitchen, her skin dewy from work, quietly sipping a glass of wine. The satisfaction on her face is the kind that can only come from the knowledge that you have created something that sustains both the bodies and the spirits of the people in your care. Indeed, Babette?s story is an argument for the idea that spending money, time, and energy cooking for friends is the best gift a home cook can give, especially if they enjoy themselves so much that they practically forget who?s behind the stove.

I can think of no more eloquent way of summarizing this ethic than Babette?s own words: ?I was able to make them happy ? when I gave of my best.? Anyone can learn to stuff a quail with fancy things; perfecting the recipe for fleeting, full-bellied happiness is a far more impressive feat, and one that any home cook worth his kosher salt should be after every time he picks up his knife.

Source: http://www.slate.com/articles/life/food/2013/07/cailles_en_sarcophage_babette_s_feast_s_richest_most_expensive_dish_made.html

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Wednesday, July 31, 2013

The Entire Premise of Jurassic Park Is Wrong Because of Mosquitoes

The Entire Premise of Jurassic Park Is Wrong Because of Mosquitoes

You're probably going to want to sit down for this one. And hold your loved ones near if you've got them, because it's time to wake up from our slumber of lies?apparently Jurassic Park is, in fact, not scientifically accurate. All because of one little, mistyped mosquito.

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Opera Mediaworks releases Q2 State of Mobile Advertising report: iOS keeps bringing more money than Android

IntoMobile writes, Opera Mediaworks released its Q2 State of Mobile Advertising report, briefing the industry on mobile monetization and advertising trends that unfolded during the period. Here are the highlights: iPhone is still a clear revenue winner, generating 36.4% of revenue compared to Android?s 27.8%. Additionally, iOS also accounts for 43.8% of impressions though Samsung?s dominance of the Android market (58.5%) makes it a strong contender. Baseball season kickoff makes Sports the No. 1 revenue generator for the quarter. Though Sports only commands a 6.5% share of the revenue generated across all?

Continue reading Opera Mediaworks releases Q2 State of Mobile Advertising report: iOS keeps bringing more money than Android at IntoMobile

Source: http://mobilitybeat.com/intomobile/124856/opera-mediaworks-releases-q2-state-of-mobile-advertising-report-ios-keeps-bringing-more-money-than-/

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From obscurity, Manning became polarizing symbol

Supporters of Army Pfc. Bradley Manning protest outside of the gates at Fort Meade, Md., Tuesday, July 30, 2013. Manning was acquitted of aiding the enemy, the most serious charge he faced, but was convicted of espionage, theft and other charges, more than three years after he spilled secrets to WikiLeaks. (AP Photo/Jose Luis Magana)

Supporters of Army Pfc. Bradley Manning protest outside of the gates at Fort Meade, Md., Tuesday, July 30, 2013. Manning was acquitted of aiding the enemy, the most serious charge he faced, but was convicted of espionage, theft and other charges, more than three years after he spilled secrets to WikiLeaks. (AP Photo/Jose Luis Magana)

Army Pfc. Bradley Manning is escorted out of a courthouse in Fort Meade, Md., Tuesday, July 30, 2013, after receiving a verdict in his court martial. Manning was acquitted of aiding the enemy ? the most serious charge he faced ? but was convicted of espionage, theft and other charges, more than three years after he spilled secrets to WikiLeaks. (AP Photo/Patrick Semansky)

In this July 30, 2013 photo, Army Pfc. Bradley Manning is escorted out of a courthouse in Fort Meade, Md. Few Americans in living memory have emerged from obscurity to become such polarizing public figures _ admired by many around the world, fiercely denigrated by many in his homeland. (AP Photo/Patrick Semansky)

FILE - In this Jan. 18, 2011 file photo, unidentified Occupy London protesters demonstrate outside the High Court following news that the City of London Corporation has won its legal bid to evict anti-capitalist protesters from outside St Paul's Cathedral, in London. Few Americans in living memory have emerged from obscurity to become such polarizing public figures _ admired by many around the world, fiercely denigrated by many in his homeland. (AP Photo/Lefteris Pitarakis, File)

FILE - In this July 26, 2013 photo, Zach Callahan, right, and supporters of U.S. Army Pfc. Bradley Manning, march outside Fort Lesley J. McNair, in Washington. Few Americans in living memory have emerged from obscurity to become such polarizing public figures _ admired by many around the world, fiercely denigrated by many in his homeland. (AP Photo/Manuel Balce Ceneta, File)

(AP) ? The honors and accolades proliferated over three years: international peace prizes, solidarity campaigns by celebrities, an effort to designate him ? in absentia, of course ? as grand marshal of San Francisco's gay pride parade.

All the while, Bradley Manning was imprisoned by the military, branded a traitor by the U.S. government and reviled by many Americans. Some called for his execution for giving troves of classified secrets to WikiLeaks for global distribution.

Few Americans in living memory have emerged from obscurity to become such polarizing public figures ? admired by many around the world, fiercely denigrated by many in his homeland.

The contrasting portraits of Manning were summarized by his defense attorney, David Coombs, during the trial that culminated Tuesday with Manning's acquittal on a charge of aiding the enemy and his conviction on charges of espionage, theft and computer fraud.

"Is Pfc. Manning somebody who is a traitor, who has no loyalty to this country, or the flag?" Coombs had asked. "Or is he a young, naive, good-intentioned soldier who had human life, in his humanist beliefs, center to his decision?

"Which side of the version is the truth?"

His supporters embraced the second of those versions, as illustrated by a full-page ad last week in The New York Times, headlined "WE ARE BRADLEY MANNING." The ad's 850 signatories included writer Alice Walker, activist intellectual Noam Chomsky, singer Joan Baez, and Daniel Ellsberg, the leaker of the Vietnam War-era Pentagon Papers who has praised Manning as a worthy heir to his legacy.

"This 25-year-old, openly gay soldier from Oklahoma does not deserve to spend one more day in prison for informing the public of our government's policies," the newspaper ad said. "We will not relent until this American hero is free."

His detractors had a different view.

"We need to get very, very serious about treason," Fox News analyst Ralph Peters said on a recent newscast. "And oh by the way, for treason ? as in the case of Bradley Manning or Edward Snowden ? you bring back the death penalty."

The lead prosecutor at Manning's trial, Maj. Ashden Fein, depicted the Army private as a "gleeful, grinning" malefactor who savored the glory of being a whistleblower.

"The only human Pfc. Manning ever cared about was himself," Fein said.

From the highest levels of the U.S. government, civilian and military leaders argued that Manning had violated pledges made to get his top secret clearance, potentially endangered U.S. agents, and made classified information accessible to America's enemies.

"Some information which is sensitive, which does affect the security of individuals and relationships, deserves to be protected and we will continue to take necessary steps to do so," said Hillary Rodham Clinton while serving as secretary of state when Manning released classified diplomatic cables.

One leaked dispatch referred to the president of Turkmenistan as "a practiced liar" and "not a very bright guy." Another said Sweden engaged in military and intelligence cooperation with the U.S. in contradiction with its public stance of nonalignment.

One of Manning's leading defenders believes he decided to reveal secrets without any expectation of fame.

"I don't think he intended to become a hero in the sense of having followers all over the world," said Emma Cape, campaign organizer for the Bradley Manning Support Project. "I do think he was intending to do the right thing, knowing his actions would affect people all over the world."

"It was very brave what he did," Cape said. "He is a hero to people not because he is Superman ... but because he's somebody who stood up for democracy and government transparency and accountability at a time when it was needed."

Widney Brown, senior director of international law and policy for Amnesty International, said Manning ? whether it was his goal or not ? had become a symbol.

"His revelations have become symbolic of challenging a post-9/11 world in which national security has gone awry," she said. "It has piqued the imagination and interest of people who are asking if 9/11 gave carte blanche for the government to do whatever it wants as long it says it's in the name of national security."

Support for Manning has been particularly notable in Europe, where he was widely viewed as a conscience-stricken whistleblower incurring the wrath of American authorities for disclosures that embarrassed them.

The Geneva-based International Peace Bureau this month awarded Manning its annual peace prize. Several European lawmakers have urged the U.S. to free him outright. Vigils and protests have regularly been held in his honor outside of U.S. embassies across the continent.

"Manning is a true patriot, not a traitor," British gay-rights activist Peter Tatchell said Tuesday. "At great personal sacrifice, he exposed grave crimes that were perpetrated and then hidden by the U.S. government and military."

With his slight build and bespectacled, boyish looks, Manning embodied neither a superhero nor arch-villain. Indeed, Widney Brown suggested his case provided a counterpoint to the macho imagery that sometimes envelops military and national security matters.

Norm Kent, a criminal defense lawyer and publisher of the South Florida Gay News, likened Manning to the Chinese man shown in an iconic photograph confronting a line of army tanks amid Beijing's Tiananmen Square protests in 1989.

"I'd like to think Manning is one of the people who rose to the moment when he was faced with a moral crisis," Kent said. "Maybe, having been a gay man and an outcast before, and understanding what it was like to be alienated, he wasn't afraid to become the little engine that could."

Steven Bucci, a foreign policy expert with the conservative Heritage Foundation, said Manning's personal traits would contribute to a mixed legacy.

"People see a troubled young man as much as a hero or a complete villain," Bucci said. "I don't think there are many people who think he's Benedict Arnold, but they think he broke the law and his reasoning is skewed. I don't know that he's going to become a folk hero except for the most rabid civil libertarian kind of folks."

Michael Ratner, president emeritus of the New York-based Center for Constitutional Rights, said he initially shared the perception that Manning was psychologically frail, but changed his view after hearing the private testify while pleading guilty to some of the charges leveled against him.

"I had an image that turned out to be completely false," Ratner said. "I was shocked by his intelligence, his politics, the firmness of his voice. It showed a person with tremendous presence."

"His plea was so moving," Ratner said. "Someday maybe people will read it and begin to understand what it means to act on your conscience."

___

Follow David Crary on Twitter at http://www.twitter.com/craryap

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-07-31-Manning-WikiLeaks-Mythology/id-4860119b9ff54e4bba913090300426c8

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Tuesday, July 30, 2013

Berlusconi faces verdict that could endanger Italian government

By Barry Moody

ROME (Reuters) - Italy's supreme court convenes on Tuesday to rule whether Silvio Berlusconi should be jailed and banned from public office for tax fraud, a verdict that could endanger Italy's shaky coalition government.

A ruling against the former prime minister would be his first definitive conviction and signal the end of an era in which he has dominated Italian politics for two decades through his media power and political skill.

It could also plunge the government - an uneasy coalition of Enrico Letta's center-left Democratic Party (PD) and Berlusconi's center-right People of Freedom (PDL) - into crisis and bring renewed uncertainty to the euro zone third's largest economy that could reverberate across the bloc.

The five judges of the Cassation Court - Italy's highest -will hear a final appeal by Berlusconi against a 1-year jail sentence and 5-year ban from office handed down by lower courts for the fraudulent purchase of broadcasting rights by his Mediaset media empire.

The court may take up to three days to deliver its ruling.

Berlusconi, 76, accuses leftwing magistrates of trying to bring him down in more than two dozen court cases since he stormed to power for the first time in 1994.

Although they are waiting for a signal from Berlusconi, PDL hawks have called for everything from a mass resignation of its government ministers to blocking Italy's motorways if the court rules against him.

Fabrizio Cicchitto, a senior PDL parliamentarian, said the media magnate had faced 30 trials. "If this is not a political use of justice what is?"

The departure of Berlusconi from parliament if he is convicted would also raise major questions about the future of his party, which depends on his charisma and wealth.

But a greater risk to the government could come from Letta's faction-ridden PD, many of whose members are already deeply unhappy with being in a coalition with their old enemy, and may refuse to continue if he is found guilty.

CHAOTIC

However, both President Giorgio Napolitano, who dragged the parties into a coalition in April after a two-month crisis that followed inconclusive elections, and Letta himself are adamant that Italy cannot afford more instability as it struggles to climb out of its worst postwar recession.

Both of the major parties may also be reluctant to precipitate an election whose result could be even more chaotic than the February vote and boost support for the populist 5-Star Movement of comedian Beppe Grillo.

Berlusconi has for months kept his hawks on a tight leash, saying the government must continue.

However, political sources say this stance was dictated by Berlusconi's lawyers, who wanted to avoid upsetting the supreme court judges. The mercurial magnate's reaction if he is found guilty is uncertain.

Berlusconi's lawyers have filed 50 objections to the supreme court, which will rule only on legal procedure and whether the previous appeal court properly justified its sentence.

The court has three choices: convict Berlusconi, acquit him or send the case back to the appeal court because of legal errors. It could also postpone a decision, probably until September - a move advocated by moderate politicians who want to avoid a summer crisis.

Even if Berlusconi is found guilty, his ban from public office depends on a vote by his peers in the Senate which could take weeks or months.

The scandal-plagued mogul is also appealing against a seven- year jail term handed down in June for abuse of office and paying for sex with Moroccan-born nightclub dancer Karima El Mahroug alias "Ruby the Heartstealer" when she was underage.

(Additional reporting by Catherine Hornby and James Mackenzie; Editing by Robin Pomeroy)

Source: http://news.yahoo.com/berlusconi-faces-verdict-could-endanger-italian-government-233240702.html

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Crash kills Texas A&M freshman lineman, Utah teen

Authorities say an 18-year-old man was the driver in a single-car crash that killed Texas A&M freshman football player Polo Manukainiu (mah-NOO'-ky-uh-noo) and a friend who was joining the Utah football team this fall.

New Mexico State Police spokesman Emmanuel Gutierrez says Siaosi Salesi Uhatafe (oo-ha-tah-feh) Jr. crashed the SUV he was driving late Monday when he over-corrected the vehicle. It rolled several times near the town of Cuba, in northern New Mexico.

The crash killed three passengers: 19-year-old Manukainiu, 13-year-old Andrew Uhatafe and 18-year-old Gaius Vaenuku, who was joining the Utes this season.

Authorities says the driver was the only one wearing his seat belt. He and his father, Salesi Uhatafe, suffered minor injuries and were the only survivors.

THIS IS A BREAKING NEWS UPDATE. Check back soon for further information. AP's earlier story is below.

Texas A&M said Tuesday that redshirt freshman Polo Manukainiu and a friend who was joining the Utah football team this fall were among three people killed in a single-car rollover crash in the high desert of northern New Mexico, stunning both schools just days before fall practices begin.

Manukainiu, a 19-year-old defensive lineman for the Aggies, and 18-year-old Utah recruit Gaius "Keio" Vaenuku were killed, officials from both schools said.

The wreck happened Monday evening on U.S. 550 near Cuba, about 85 miles north of Albuquerque, apparently as the group was returning to suburban Dallas, where three of them had ties to prep football power Trinity High School in Euless.

New Mexico state police said Manukainiu and Vaenuku were passengers in a southbound 2002 Toyota Sequoia that drifted off the sagebrush-lined highway, according to Texas A&M. The driver overcorrected and the vehicle rolled several times.

Alcohol wasn't involved and it appeared that the driver, who was not immediately identified, was the only one wearing a seatbelt, authorities said.

Manukainiu and passenger Andrew "Lolo" Uhatafe died at the scene after they were ejected from the vehicle, the Texas A&M statement said. Vaenuku was pronounced dead in an ambulance that responded to the accident.

Survivors included Salesi Uhatafe and his son Salesi Uhatafe Jr., an incoming freshman football player for Utah and a stepbrother of Manukainiu. Both suffered only minor injuries, authorities said.

Manukainiu had apparently traveled to Salt Lake City for some relaxation, tweeting Sunday: "It's always good to get away from the Texas Heat for the weekend. Utah got that breezeeeeeee."

On Monday, hours before the accident, he tweeted: "22 hour drive back to Texas on no sleep. Oh my."

Manukainiu played football at Trinity High School in Euless, west of Dallas, and was part of the Aggies' 2012 signing class. He was a recreation, parks and tourism science major, the school said, and is survived by his mother, Lima Uhatafe of Euless.

"We lost a terrific young man," Texas A&M coach Kevin Sumlin said. "Polo was loved by his teammates and coaches. Anyone who came in contact with him was struck by his sense of humor and smile. My heart aches for his mom and family members."

Texas A&M finished last season ranked No. 5 after an 11-2 season, their first in the Southeastern Conference. They were led by quarterback Johnny Manziel, who became the first freshman to win the Heisman Trophy, and are expected to be highly ranked again this year.

"Heart hurts waking up to news about Polo," Manziel tweeted on Tuesday. "I think I speak for everyone on our team when I say we love you brother you will be missed."

It is the second such tragedy for Texas A&M in less than two years: Senior offensive lineman Joseph Villavisencio, 22, was killed in a December 2011 car accident after veering head-on into the path of an 18-wheeler 40 miles from College Station. He had spent part of that day delivering gifts to families at a local shelter. Manziel mentioned Villavisencio during his Heisman acceptance speech last year.

Vaenuku was a defensive tackle who had planned to play one year at Utah before going on a two-year Mormon mission, the Deseret News of Salt Lake City reported in January when he committed.

"Everyone who knew Gaius is heartbroken today," Utah coach Kyle Whittingham said. "He was the kind of young man who lit up a room and his future in football and life had no boundaries. Words cannot express our devastation over the loss of Gaius."

Vaenuku was a member of The Church of Jesus Christ of Latter-day Saints and considered playing at church-owned Brigham Young but he said he felt more at home in Salt Lake City playing for the Utes. His bio on the Utah website says Vaenuku he had three brothers and three sisters and enjoyed acting and singing.

The news stunned Trinity High in Euless, where Manukainiu, Vaenuku and Uhatafe Jr. all played football. The team has been one of the best in Texas in recent years, with three state titles in a span of five seasons from 2005-09 and a trip to the championship game in 2010.

Principal Mike Harris said the deaths have affected a majority of the Euless community, where there is a tight-knit Polynesian community.

"They were students with bright smiles that everybody knew and everybody loved," the principal said.

Texas A&M associate athletic director Alan Cannon said Manukainiu was known for his sense of humor and "will be sorely missed as a person you enjoyed being around." He said the football staff was working Tuesday to notify teammates of his death. Players are scheduled to report to campus Sunday to begin practicing for the upcoming season.

Cannon said Manukainiu was to wear jersey No. 90 and that it was too early to determine if players will affix the number to their uniforms as a tribute. The NCAA must approve any such recognition, Cannon said.

---

Associated Press writers Brady McCombs in Salt Lake City and David Warren and Uriel Garcia in Dallas contributed to this report.

Source: http://hosted.ap.org/dynamic/stories/F/FBC_TEXAS_AM_PLAYER_KILLED?SITE=KING&SECTION=HOME&TEMPLATE=DEFAULT

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Monday, July 29, 2013

Same-Day Delivery Is Great for Everybody? Except the Deliverers

Same-Day Delivery Is Great for Everybody? Except the Deliverers

We've already adjusted to the consumer utopia of buying just about everything online with a single click, but waiting for it to show up is still the hardest part. eBay Now pulled it off in a few places, and it's not easy; just ask the couriers who are making it happen.

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Dr. Bernice A. King Delivers Commencement Address at Kaplan University?s 2013 Summer Graduation

More than 6,000 degrees conferred to online students

CHICAGO--(BUSINESS WIRE)--Kaplan University?s 2013 Summer Commencement was held today in Chicago at the historic Chicago Theatre. The ceremony celebrated the hard work, perseverance and achievements of more than 6,000 graduates who earned Associate, Bachelor and Master Degrees from Kaplan University?s Schools of Arts and Sciences, Business, Education, Health Sciences, Information Technology, Legal Studies, Nursing and Public Service.

?Fifty years ago, my father delivered his ?I Have a Dream?

Dr. Bernice A. King, daughter of human rights leaders Dr. Martin L. King, Jr. and Coretta Scott King, delivered the keynote address at each of the two ceremonies held today, addressing more than 700 graduates in attendance and thousands more watching and celebrating via a live webcast. She called on the graduates to continue to pursue their dreams, strive for excellence, and use their education and skills to make a positive impact in the lives of others.

?Fifty years ago, my father delivered his ?I Have a Dream? speech. As you continue to fulfill your dreams, hold on to the tenacity and commitment that brought you to this defining moment. My father understood that intelligence plus character is the true goal of education. He was an educated leader with character and integrity. He was an ordinary person, who had an extraordinary impact on the world. Our world is in great need of more leaders like him and you have what the world is waiting for. I implore you to take your degrees and answer the call!? said Dr. King.

An ordained minister and attorney, Dr. King is the chief executive officer of The King Center in Atlanta, Georgia. She is also the author of the book, ?Hard Questions, Heart Answers.?

Kaplan University President Dr. Wade Dyke congratulated the graduates.

?While your individual journeys to this day and stage began on different days and stages in your lives, you have much in common, including a unifying desire to change your lives and others through the path that is education,? said Dr. Dyke. ?As you continue on your life?s journey, take each step with the same motivation and enthusiasm to make a positive difference.?

Earlier this year, some 7,000 degrees were conferred to online students at Kaplan University?s Winter Commencement in Miami, Fla.

About Kaplan University

Kaplan University offers a different school of thought for higher education. It strives to help adult students unlock their talent by providing a practical, student-centered education that prepares them for careers in some of the fastest-growing industries. The University, which has its main campus in Davenport, Iowa, and its headquarters in Chicago, is accredited by The Higher Learning Commission (www.ncahlc.org) and is a member of the North Central Association of Colleges and Schools. Kaplan University serves approximately 49,000 online and campus-based students. The University has 11 campuses in Iowa, Nebraska, Maryland and Maine, and Kaplan University Learning Centers in?Maryland,?Wisconsin,?Indiana,?Missouri?and?Florida.

Kaplan University?is?part of Kaplan Higher Education Group and Kaplan, Inc., a leading international provider of educational and career services for individuals, schools and businesses.?Kaplan, Inc. serves approximately 67,000 students online and through approximately 70 campus-based schools across the United States. Kaplan?s higher education schools offer a spectrum of academic opportunities, from certificates and diplomas to graduate and professional degrees, including a juris doctor degree.?Kaplan serves students of all ages through a wide array of offerings including higher education, test preparation, professional training and programs for kids in grades K-12. Kaplan, Inc., is a subsidiary of The Washington Post Company and its largest division. For more information, visit?www.kaplanuniversity.edu.

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San Francisco To Mitigate Growth and Conserve Energy Resources with Eco-Districts

San Francisco Neighborhood

Can Eco-Districts help a major city grow sustainably while conserving energy resources? San Francisco?s about to find out.

San Francisco already has a lot of distinct neighborhoods?Chinatown, the Castro,?Haight-Ashbury. Each has its own distinct personality, type of resident, and geographical area. These fascinating neighborhoods formed organically over time, building a strong sense of community that?s almost like tiny cities within a city.

Now, the City of San Francisco wants to manufacture a new kind of district in hopes of?reducing water consumption and waste, and enhancing community-scale energy resources. They will, unsurprisingly, be called Ec0-Districts, and if successful, they could help San Francisco continue to grow without increasing its negative environmental impact.

?To aid in the fulfillment of these goals, the program is implementing a tool called Eco-Districts ? a community of property owners, businesses and residents within a neighborhood that collaborate to develop and initiate sustainable development projects in their area,? reports ArchDaily. ?Using a set of performance metrics, neighborhoods can shape their projects with custom strategies for their community.?

So what exactly will these Eco-Districts look like? Well according to the SF Planning Department, there will be four different types of Eco-District, and true to form, they all have creative names.

Eco-District Central Corridor

The Blank Slate

In a Blank Slate district, most of the land is?undeveloped and typically owned by a single property owner. With very little existing development to work around, this type of district enables??horizontal infrastructure development to be implemented in advance of vertical development to help optimize Eco-District goals.?

The Patchwork Quilt

In a Quilt District, there is both undeveloped, underdeveloped, and developed land, owned by different property owners implementing development projects under different time frames. This presents more of a challenge than the Blank Slate. The goal with a Quilt is to align ?development time frames to maximize opportunities to meet environmental goals.? The community will be encouraged ?to build on its existing character and to integrate the physical qualities of the area as part of its character.? (San Francisco?s Central Corridor is an example of this type of Eco-District in action.)

The Strengthened Neighborhood

This is one of the most exciting types of Eco-Districts, because it?s a neighborhood that?s already at capacity, but perhaps not operating at optimal efficiency with regards to energy resources. In this district,?the Office of Economic and Workforce Development?s?Invest in Neighborhoods Initiative, would use strategies of ?tactical urbanism? to ?bolster distinctive character and support eco-friendly behavior.?

The Industrial Network

Cities can?t be all parks and courtyards. In every metropolis, there is a section dedicated to industrial purposes, where power is made, and where distribution and repair of all types of services for energy resources occurs.?Aligning these industries so that their operating and distribution systems can work more efficiently is the primary focus of the Industrial Eco-District.

In each of these neighborhoods, similar tactics to increase sustainability will be deployed, all in line with the waste-reduction goals of the city and state. Coordinated neighborhoods could take advantage of group purchasing of solar power at lower rates, or perhaps even a community-shared solar installation.

?An eco-district could also set up an?efficient district energy system, which produces steam, heated water and chilled water at a central plant and distributes the energy to multiple connected buildings, so they do not need to have their own boilers or chillers,? writes Sustainable Development Policy Director Laura Tam. ?An eco-district organization could facilitate water reuse between properties, too, such as harvesting rainwater from multiple properties to irrigate a neighborhood park or street landscaping.?

The possibilities, when communities are organized and invited to participate in their own planning process, are endless. Learn more about how other cities?Austin, Boston and Seattle?have already put Eco-Districts to work at ecodistricts.org.

Images: Wikimedia Commons,?Jihee Chung, SWA Group

Source: http://ecosalon.com/san-francisco-to-conserve-energy-resources-with-eco-districts/

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